publications (selected)

For a full list please go to PUBMED

• Atchou K*, Berger BM*, Heussler V, Ochsenreiter T. Pre-gelation staining expansion microscopy (PS-ExM) for visualisation of the Plasmodium liver stage. J Cell Sci. 2023 Nov 9:jcs.261377. doi: 10.1242/jcs.261377. Epub ahead of print. PMID: 37942994. *These authors contributed equally to the work

• Amodeo S, Bregy I, Hoffmann A, Fradera-Sola A, Kern M, Baudouin H, Zuber B, Butter F, Ochsenreiter T. Characterization of two novel proteins involved in mitochondrial DNA anchoring in Trypanosoma brucei. PLOS Pathogens. 2023 19(7): e1011486. PMID: 37459364

• Amodeo S, Bregy I, Ochsenreiter T. Mitochondrial genome maintenance - the kinetoplast story. FEMS Microbiol Rev. 2022 Nov 30:fuac047. doi: 10.1093/femsre/fuac047. PMID: 36449697

• Aeschlimann S, Kalichava A, Schimanski B, Berger BM, Jetishi C, Stettler P, Ochsenreiter T,* Schneider A. * Single p197 molecules of the mitochondrial genome segregation system of Trypanosoma brucei determine the distance between basal body and outer membrane. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2204294119. doi: 10.1073/pnas.2204294119. Epub 2022 Sep 26. PMID: 36161893; PMCID: PMC9546609. *co-corresponding authors

• Dewar CE, Oeljeklaus S, Mani J, Mühlhäuser WWD, von Känel C, Zimmermann J, Ochsenreiter T, Warscheid B, Schneider A. Mistargeting of aggregation prone mitochondrial proteins activates a nucleus-mediated posttranscriptional quality control pathway in trypanosomes. Nat Commun. 2022 Jun 2;13(1):3084. doi: 10.1038/s41467-022-30748-z. PMID: 35654893; PMCID: PMC9163028.

• Kalichava A, Ochsenreiter T. Ultrastructure expansion microscopy in Trypanosoma brucei. Open Biol. 2021 Oct;11(10):210132. doi: 10.1098/rsob.210132. Epub 2021 Oct 13. PMID: 34637654; PMCID: PMC8510702.

• Amodeo S, Kalichava A, Fradera-Sola A, Bertiaux-Lequoy E, Guichard P, Butter F, Ochsenreiter T. Characterization of the novel mitochondrial genome segregation factor TAP110 in Trypanosoma brucei. J Cell Sci. 2021 134: jcs254300 doi: 10.1242/jcs.254300 8 March 2021 - accompanied by First Person Interview

• Baudouin HCM, Pfeiffer L, Ochsenreiter T. A comparison of three approaches for the discovery of novel tripartite attachment complex proteins in Trypanosoma brucei. PLoS Negl Trop Dis. 2020 Sep 16;14(9):e0008568. doi: 10.1371/journal.pntd.0008568. PMID: 32936798; PMCID: PMC7521757.

• Aphasizheva I, Alfonzo J, Carnes J, Cestari I, Cruz-Reyes J, Göringer HU, Hajduk S, Lukeš J, Madison-Antenucci S, Maslov DA, McDermott SM, Ochsenreiter T, Read LK, Salavati R, Schnaufer A, Schneider A, Simpson L, Stuart K, Yurchenko V, Zhou ZH, Zíková A, Zhang L, Zimmer S, Aphasizhev R. Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes. Trends Parasitol. 2020 Apr;36(4):337-355. doi: 10.1016/j.pt.2020.01.006. PMID: 32191849

• Cooper S, Wadsworth ES, Ochsenreiter T, Ivens A, Savill NJ, Schnaufer A. Assembly and annotation of the mitochondrial minicircle genome of a differentiation-competent strain of Trypanosoma brucei. Nucleic Acids Res. 2019 Dec 2;47(21):11304-11325. doi: 10.1093/nar/gkz928. PMID: 31665448; PMCID:
  PMC6868439.

• Schneider A, Ochsenreiter T. Failure is not an option - mitochondrial genome segregation in trypanosomes. J Cell Sci. 2018 Sep 17;131(18). pii: jcs221820. doi: 10.1242/jcs.221820. PMID: 30224426.

• Jojic B, Amodeo S, Bregy I, Ochsenreiter T. Distinct 3' UTRs regulate the life-cycle-specific expression of two TCTP paralogs in Trypanosoma brucei. J Cell Sci. 2018 May 10;131(9). pii: jcs206417. doi: 10.1242/jcs.206417. PMID: 29661850; PMCID: PMC5992589.

• Amodeo S, Jakob M, Ochsenreiter T. Characterization of the novel mitochondrial genome replication factor MiRF172 in Trypanosoma brucei. J Cell Sci. 2018 Apr 25;131(8). pii: jcs211730. doi: 10.1242/jcs.211730. PMID: 29626111; PMCID: PMC5963845.

• Hoffmann A, Käser S, Jakob M, Amodeo S, Peitsch C, Týč J, Vaughan S, Zuber B, Schneider A, Ochsenreiter T. Molecular model of the mitochondrial genome segregation machinery in Trypanosoma brucei. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1809-E1818. doi: 10.1073/pnas.1716582115. Epub 2018 Feb 6. PMID: 29434039; PMCID: PMC5828607.

• Jakob M, Hoffmann A, Amodeo S, Peitsch C, Zuber B, Ochsenreiter T. Mitochondrial growth during the cell cycle of Trypanosoma brucei bloodstream forms. Sci Rep. 2016 Nov 22;6:36565. doi: 10.1038/srep36565. PMID: 27874016; PMCID: PMC5118809.

• Trikin R, Doiron N, Hoffmann A, Haenni B, Jakob M, Schnaufer A, Schimanski B, Zuber B, Ochsenreiter T. TAC102 Is a Novel Component of the Mitochondrial Genome Segregation Machinery in Trypanosomes. PLoS Pathog. 2016 May 11;12(5):e1005586. doi: 10.1371/journal.ppat.1005586. eCollection 2016 May. 2016 Jul;12(7):e1005750. PMID: 27168148; PMCID: PMC4864229.

• Schnarwiler F, Niemann M, Doiron N, Harsman A, Käser S, Mani J, Chanfon A, Dewar CE, Oeljeklaus S, Jackson CB, Pusnik M, Schmidt O, Meisinger C, Hiller S, Warscheid B, Schnaufer AC, Ochsenreiter T, Schneider A. Trypanosomal TAC40 constitutes a novel subclass of mitochondrial β-barrel proteins specialized in mitochondrial genome inheritance. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7624-9. doi: 10.1073/pnas.1404854111. Epub 2014 May 12. PMID: 24821793; PMCID: PMC4040615.

• Gunasekera K, Wüthrich D, Braga-Lagache S, Heller M, Ochsenreiter T. Proteome remodelling during development from blood to insect-form Trypanosoma brucei quantified by SILAC and mass spectrometry. BMC Genomics. 2012 Oct 16;13:556. doi: 10.1186/1471-2164-13-556. PMID: 23067041; PMCID: PMC3545838.

• Rettig J, Wang Y, Schneider A, Ochsenreiter T. Dual targeting of isoleucyl-tRNA synthetase in Trypanosoma brucei is mediated through alternative trans-splicing. Nucleic Acids Res. 2012 Feb;40(3):1299-306. doi: 10.1093/nar/gkr794. Epub 2011 Oct 5. PMID: 21976735; PMCID: PMC3273800

• Siegel TN, Gunasekera K, Cross GA, Ochsenreiter T. Gene expression in Trypanosoma brucei: lessons from high-throughput RNA sequencing. Trends Parasitol. 2011 Oct;27(10):434-41. doi: 10.1016/j.pt.2011.05.006. Epub 2011 Jul 6. Review. PMID: 21737348; PMCID: PMC3178736.

• Nilsson D, Gunasekera K, Mani J, Osteras M, Farinelli L, Baerlocher L, Roditi I, Ochsenreiter T. Spliced leader trapping reveals widespread alternative splicing patterns in the highly dynamic transcriptome of Trypanosoma brucei. PLoS Pathog. 2010 Aug 5;6(8):e1001037. doi: 10.1371/journal.ppat.1001037. PMID: 20700444; PMCID: PMC2916883.

• Zhang X, Cui J, Nilsson D, Gunasekera K, Chanfon A, Song X, Wang H, Xu Y, Ochsenreiter T. The Trypanosoma brucei MitoCarta and its regulation and splicing pattern during development. Nucleic Acids Res. 2010 Nov;38(21):7378-87. doi: 10.1093/nar/gkq618. Epub 2010 Jul 26. PMID: 20660476; PMCID: PMC2995047.

• Hajduk S, Ochsenreiter T. RNA editing in kinetoplastids. RNA Biol. 2010 Mar-Apr;7(2):229-36. Epub 2010 Mar 1. PubMed PMID: 20220308.